Innovative Toxicity Assays of Pollutants, Therapeutics, and Drugs (SBIR [R43/R44])

Innovative Toxicity Assays of Pollutants, Therapeutics, and Drugs (SBIR [R43/R44])

Synopsis

The synopsis for this grant opportunity is detailed below, following this paragraph. This synopsis contains all of the updates to this document that have been posted as of 10/07/2008 . If updates have been made to the opportunity synopsis, update information is provided below the synopsis.
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Document Type: Grants Notice
Funding Opportunity Number: PA-09-006
Opportunity Category: Discretionary
Posted Date: Oct 07, 2008
Creation Date: Oct 08, 2008
Original Closing Date for Applications: Sep 07, 2009
Current Closing Date for Applications: Sep 07, 2009
Archive Date: Oct 08, 2009
Funding Instrument Type: Grant

Category of Funding Activity: Health
Food and Nutrition
Education
Environment

Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:
CFDA Number(s): 93.113 -- Environmental Health
93.173 -- Research Related to Deafness and Communication Disorders
93.361 -- Nursing Research
93.389 -- National Center for Research Resources
93.837 -- Heart and Vascular Diseases Research
93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research
93.847 -- Diabetes, Endocrinology and Metabolism Research
93.848 -- Digestive Diseases and Nutrition Research
93.849 -- Kidney Diseases, Urology and Hematology Research
93.859 -- Biomedical Research and Research Training
93.867 -- Vision Research
Cost Sharing or Matching Requirement: No

Eligible Applicants
Small businesses

Additional Information on Eligibility:

Agency Name
National Institutes of Health
Description
-Purpose. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involves the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. -Mechanism of Support. This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-007, which encourages applications under the Small Business Technology Transfer (STTR) (R41/R42) grant mechanisms.

Link to Full Announcement
http://grants.nih.gov/grants/guide/pa-files/PA-09-006.html
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Synopsis Modification History
There are currently no modifications for this opportunity.